| 1 | Emmaus High School | Emmaus, Pennsylvania | 9-0-0 | 2 | 9/20 vs Freedom- 13-0 W, 9/22 vs East Stroudsburg South- 12-0 W, 9/25 @Hershey- 5-0 W, 9/27 @Central Bucks East- 8-0 W | |
| 2 | Villa Maria Academy | Malvern, Pennsylvania | 8-1-0 | 11 | 9/21 vs Sacred Heart Academy- 11-0 W, 9/24 vs Eastern Regional (NJ)- 3-0 W, 9/25 vs Assumption (KY)- 2-1 W, 9/27 @Villa Joseph Marie- 8-0 W | |
| 3 | Episcopal Academy | Newtown Square, Pennsylvania | 7-1-0 | 1 | 9/21 vs Germantown Academy- 6-0 W, 9/25 vs Eastern Regional (NJ)- 1-3 L, 9/26 vs Norfolk Academy (VA)- 2-1 W OT | |
| 4 | Lower Dauphin High School | Hummelstown, Pennsylvania | 10-0-0 | 3 | 9/20 @East Pennsboro- 4-1 W, 9/22 @Mechanicsburg- 2-1 W | |
| 5 | The Hill School | Pottstown, Pennsylvania | 6-1-0 | 4 | 9/24 vs Garrison Forest (MD)- 1-0 W, 9/25 vs Kinkaid School (KY)- 8-3 W | |
| 6 | Wyoming Seminary | Kingston, Pennsylvania | 6-0-0 | 5 | 9/20 @Delaware Valley- 9-0 W, 9/22 vs Wyoming Area- 4-0 W, 9/25 vs Selinsgrove- 8-0 W, 9/27 vs Wilkes-Barre- 13-0 W | |
| 7 | Palmyra Area High School | Palmyra, Pennsylvania | 9-1-0 | 6 | 9/20 @Hershey- 5-0 W, 9/22 @Red Land- 7-0 W, 9/23 vs Berks Catholic- 9-0 W, 9/25 vs Dallastown- 5-0 W, 9/25 vs Central Dauphin- 6-1 W | |
| 8 | Oley Valley High School | Oley, Pennsylvania | 10-0-0 | 8 | 9/20 @Wyomissing- 8-0 W, 9/22 @Hamburg- 6-0 W, 9/24 vs Methacton- 4-1 W, 9/25 @Lampeter-Strasburg- 1-0 W, 9/27 @Kutztown- 7-0 W | |
| 9 | Twin Valley High School | Elverson, Pennsylvania | 9-1-0 | 9 | 9/20 vs Downingtown West- 6-1 W, 9/22 vs Muhlenberg- 11-0 W, 9/25 @Daniel Boone- 7-1 W, 9/27 @Conrad Weiser- 9-0 W | |
| 10 | Conestoga High School | Berwyn, Pennsylvania | 6-1-0 | 10 | 9/21 vs Strath Haven- 9-0 W, 9/25 vs Oak Knoll (NJ)- 0-2 L, 9/26 vs Garrison Forest (MD)- 4-2 W | |
| 11 | Wyoming Area High School | Exeter, Pennsylvania | 6-1-0 | 7 | 9/20 vs Crestwood- 2-1 W, 9/22 vs Wyoming Seminary- 0-4 L, 9/25 vs Bloomsburg- 2-0 W, 9/27 vs Dallas- 1-0 W | |
| 12 | Greenwood High School | Millerstown, Pennsylvania | 6-0-0 | 12 | None | |
| 13 | Garnet Valley High School | Glen Mills, Pennsylvania | 8-0-0 | 14 | 9/21 vs Ridley- 5-0 W, 9/23 @Marple Newtown- 11-0 W | |
| 14 | Gwynedd Mercy Academy High School | Gwynedd Valley, Pennsylvania | 6-2-0 | 15 | 9/21 @Merion Mercy- 3-2 W, 9/27 vs Penncrest- 15-1 W | |
| 15 | Mechanicsburg High School | Mechanicsburg, Pennsylvania | 7-3-0 | 16 | 9/20 @Red Land- 5-2 W, 9/22 vs Lower Dauphin- 1-2 L, 9/23 vs Milton Hershey- 10-0 W, 9/27 vs Red Land- 1-0 W | |
| 16 | Wilson High School | West Lawn, Pennsylvania | 7-2-0 | 19 | 9/20 @Reading- 4-0 W, 9/22 @Conrad Weiser- 7-1 W, 9/25 vs Berks Catholic- 6-0 W | |
| 17 | Parkland High School | Allentown, Pennsylvania | 10-0-0 | 20 | 9/20 @East Stroudsburg North- 8-0 W, 9/22 @Liberty- 3-0 W, 9/24 @Whitehall- 5-0 W | |
| 18 | Academy of Notre Dame de Namur | Villanova, Pennsylvania | 5-2-0 | OC | 9/20 vs Bronner & Prendergast- 9-0 W, 9/24 vs Kingsway Regional (NJ)- 0-1 L, 9/25 vs Sacred Heart Greenwich (CT)- 2-1 W | |
| 19 | Penn Manor High School | Millersville, Pennsylvania | 10-1-0 | 13 | 9/21 @Hempfield- 3-1 W, 9/23 vs Warwick- 0- 1 L, 9/27 vs Cedar Crest- 3-0 W | |
| 20 | Easton Area High School | Easton, Pennsylania | 6-2-0 | OC | 9/20 @Northampton- 3-0 W, 9/22 vs Freedom- 9-0 W, 9/24 @East Stroudsburg South- 12-0 W | |
| | | | | | |
| OC | Crestwood High School | Mountain Top, Pennsylvania | 7-2-0 | OC | 9/20 vs Wyoming Area- 1-2 L, 9/22 @Lackawanna Trail- 3-2 W, 9/27 vs Honesdale- 4-0 W | |
| OC | Cumberland Valley High School | Mechanicsburg, Pennsylvania | 6-1-0 | OC | 9/20 vs Chambersburg- 5-0 W, 9/22 @Carlisle- 3-0 W, 9/25 @Mifflin County- 4-0 W | |
| OC | Downingtown West High School | Downingtown, Pennsylvania | 7-3-0 | OC | 9/20 @Twin Valley- 1-6 L, 9/21 vs Bishop Shanahan- 8-1 W, 9/23 vs Unionville- 10-1 W, 9/25 vs Radnor- 4-1 W, 9/27 @Downingtown East- 5-4 W | |
| OC | Great Valley High School | Malvern, Pennsylvania | 7-1-0 | NR | 9/21 vs Kennett- 3-1 W, 9/23 vs WC East- 3-1 W, 9/25 vs OJR- 6-0 W | |
| OC | Hershey High School | Hershey, Pennsylvania | 5-5-1 | 18 | 9/20 vs Palmyra- 0-5 L, 9/22 vs East Pennsboro- 0-0 T, 9/25 vs Emmaus- 0-5 L, 9/28 @Red Land- 1-0 W | |
| OC | Kennett High School | Kennett Square, Pennsylvania | 7-1-0 | OC | 9/21 @Great Valley- 1-3 L, 9/24 vs Lower Merion- 10-0 W, 9/27 vs Pottsgrove- 9-0 W | |
| OC | Souderton Area High School | Souderton, Pennsylvania | 7-1-0 | OC | 9/20 vs Pennridge- 3-0 W, 9/23 @CB West- 3-0 W, 9/24 vs Council Rock North- 2-0 W | |
2021 PENNSYLVANIA REGION HIGH SCHOOL
