| 1 | Episcopal Academy | Newtown Square, Pennsylvania | 2-0-0 | 1 | 9/3 vs Gwynedd Mercy Academy- 7-5 W, 9/10 vs Cardinal O'Hara- 6-0 W |
| 2 | Emmaus High School | Emmaus, Pennsylvania | 3-0-0 | 2 | 9/4 @Pocono Mountain East- 3-1 W, 9/7 vs Bethlehem Catholic- 13-0 W, 9/9 vs Hazleton Area- 9-0 W |
| 3 | The Hill School | Pottstown, Pennsylvania | 3-0-0 | 3 | 9/8 vs Archbishop Carroll- 4-0 W, 9/11 @Charlotte Country Day School (NC)- 8-0 W, 9/12 @Providence Day School (NC)- 4-3 W |
| 4 | Wyoming Seminary | Kingston, Pennsylvania | 0-0-0 | 4 | None |
| 5 | Lower Dauphin High School | Hummelstown, Pennsylvania | 5-0-0 | 6 | 9/3 vs WVW- 3-0 W, 9/7 vs Mechanicsburg- 3-2 W, 9/9 @Palmyra- 1-0 W, 9/11 vs Hempfield- 5-0 W, 9/11 vs Dallastown- 6-1 W |
| 6 | Palmyra Area High School | Palmyra, Pennsylvania | 1-1-0 | 5 | 9/7 vs Red Land- 3-0 W, 9/9 vs Lower Dauphin- 0-1 L |
| 7 | Wyoming Area High School | Exeter, Pennsylvania | 1-0-0 | 8 | 9/4 @Lewisburg- 3-1 W |
| 8 | Twin Valley High School | Elverson, Pennsylvania | 3-0-0 | 11 | 9/3 @Coatesville- 6-0 W, 9/8 @Wilson- 3-2 W, 9/10 vs Exeter- 9-2 W |
| 9 | Oley Valley High School | Oley, Pennsylvania | 3-0-0 | 10 | 9/4 @Stroudsburg- 6-1 W, 9/7 vs Upper Perkiomen- 2-1 W, 9/8 @Fleetwood- 4-0 W |
| 10 | Wilson High School | West Lawn, Pennsylvania | 3-1-0 | 7 | 9/3 @Daniel Boone- 4-0 W, 9/4 @OJR- 5-1 W, 9/8 vs Twin Valley- 2-3 L, 9/11 vs Conestoga Valley- 5-0 W |
| 11 | Conestoga High School | Berwyn, Pennsylvania | 3-0-0 | 12 | 9/3 vs Great Valley- 3-1 W, 9/8 @Downingtown West- 3-2 W, 9/10 vs Radnor- 4-1 W |
| 12 | Villa Maria Academy | Malvern, Pennsylvania | 2-0-0 | 13 | 9/8 vs Villa Joseph Marie- 17-0 W, 9/10 @Mt St Joseph- 10-1 W |
| 13 | Greenwood High School | Millerstown, Pennsylvania | 4-0-0 | 19 | 9/4 vs Susquenita- 4-2 W, 9/4 vs Newport- 7-1 W, 9/7 vs Newport- 2-1 W, 9/9 @Susquenita- 2-1 W, 9/11 @Donegal- 6-0 W |
| 14 | Gwynedd Mercy Academy High School | Gwynedd Valley, Pennsylvania | 2-1-0 | 20 | 9/3 @Episcopal Academy- 5-7 L, 9/8 @Sacred Heart Academy- 11-0 W, 9/10 @Villa Joseph Marie- 12-1 W |
| 15 | Penn Manor High School | Millersville, Pennsylvania | 5-0-0 | OC | 9/3 @Lampeter Strasburg- 2-1 W, 9/8 vs Manheim Central- 1-0 W, 9/10 @Donegal- 3-1 W, 9/11 vs Manheim Twp- 1-0 W, 9/11 vs Hershey- 2-1 W |
| 16 | Central Bucks East High School | Doylestown, Pennsylvania | 1-0-0 | 16 | 9/10 vs Pennridge- 5-2 W |
| 17 | Central Dauphin HIgh School | Harrisburg, Pennsylvania | 1-0-0 | 17 | 9/11 vs Susqhehannock- 2-1 W |
| 18 | Selinsgrove Area High School | Selinsgrove, Pennsylvania | 2-0-0 | OC | 9/9 @Mifflinburg- 5-1 W, 9/11 vs WVW- 3-2 W |
| 19 | Garnet Valley High School | Glen Mills, Pennsylvania | 4-0-0 | OC | 9/3 @WC Rustin- 3-0 W, 9/7 vs WC Henderson- 3-0 W, 9/9 vs Harriton- 11-0 W, 9/11 vs Unionville- 6-1 W |
| 20 | Mechanicsburg High School | Mechanicsburg, Pennsylvania | 3-1-0 | NR | 9/4 @New Oxford- 7-0 W, 9/4 @Big Spring- 5-0 W, 9/7 @Lower Dauphin- 2-3 L, 9/9 @East Pennsboro- 2-1 W |
| | | | | |
| OC | Academy of Notre Dame de Namur | Villanova, Pennsylvania | 1-0-0 | OC | 9/8 vs Cardinal O'Hara- 4-1 W |
| OC | Downingtown West High School | Downingtown, Pennsylvania | 1-1-0 | OC | 9/8 vs Conestoga- 2-3 L, 9/9 @Avon Grove- 7-0 W |
| OC | Fleetwood Area High School | Fleetwood, Pennsylvania | 2-1-0 | OC | 9/4 @Exeter- 5-1 W, 9/8 vs Oley Valley- 0-4 L, 9/11 @Lehighton- 5-0 W |
| OC | Kennett High School | Kennett Square, Pennsylvania | 3-0-0 | NR | 9/3 vs Phoenixville- 4-0 W, 9/7 vs Perkiomen Valley- 3-0 W, 9/9 vs Unionville- 3-1 W |
| OC | North Penn High School | Lansdale, Pennsylvania | 2-0-0 | NR | 9/3 vs Methacton- 2-1 W, 9/9 @CB West- 10-2 W |
| OC | Hershey High School | Hershey, Pennsylvania | 3-2-0 | 14 | 9/3 vs Conestoga Valley- 2-1 W, 9/7 @East Pennsboro- 4-2 W, 9/9 vs Red Land- 0-1 L,9/11 vs Penn Manor- 3-4 L, 9/11 vs Central York- 4-1 W |
| OC | Red Land High School | Lewisberry, Pennsylvania | 1-1-0 | NR | 9/7 @Palmyra- 0-3 L, 9/9 @Hershey- 1-0 W |
| OC | Wyoming Valley West High School | Plymouth, Pennsylvania | 0-2-0 | 9 | 9/3 @Lower Dauphin- 0-3 L, 9/11 @Selinsgrove- 2-3 L |
2021 PENNSYLVANIA REGION HIGH SCHOOL
