| 1 | Eastern Regional High School | Voorhees, New Jersey | 24-2-0 | Group 4 State Champions, Tournament of Champions Winner |
| 2 | Oak Knoll School | Summit, New Jersey | 23-3-0 | Non-Public State Champions, Tournament of Champions Runner-Up |
| 3 | West Essex Regional High School | Caldwell, New Jersey | 23-3-0 | Group 2 State Champions, Tournament of Champions Semifinalist |
| 4 | Camden Catholic High School | Cherry Hill, New Jersey | 21-3-0 | Non-Public State Runner-Up |
| 5 | Kingsway Regional High School | Woolwich Township, New Jersey | 19-3-0 | South Jersey Group 4 Runner-Up |
| 6 | North Hunterdon High School | Annandale, New Jersey | 21-2-0 | Group 3 State Champions, Tournament of Champions Semifinalist |
| 7 | Shore Regional High School | West Long Branch, New Jersey | 25-2-0 | Group 1 State Champions, Tournament of Champions Quaterfinalist |
| 8 | Moorestown High School | Moorestown, New Jersey | 13-7-1 | Group 3 State Runner-Up |
| 9 | Bishop Eustace Prep | Pennsauken Township, New Jersey | 16-6-0 | Non-Public State Runner-Up |
| 10 | Seneca High School | Tabernacle, New Jersey | 16-7-1 | Group 2 State Runner-Up |
| 11 | Haddon Heights High School | Haddon Heights, New Jersey | 22-1-0 | South Jersey Group 2 Runner-Up |
| 12 | Cherokee High School | Marlton, New Jersey | 14-6-0 | South Jersey Group 4 Quarterfinalist |
| 13 | Ocean City High School | Ocean City, New Jersey | 20-3-0 | South Jersey Group 3 Runner-Up |
| 14 | Kent Place School | Summit, New Jersey | 18-4-0 | Non-Public North Runner-Up |
| 15 | Point Pleasant Boro High School | Point Pleasant, New Jersey | 21-2-0 | South Jersey Group 2 Quarterfinalist |
| 16 | Shawnee High School | Medford, New Jersey | 10-8-1 | South Jersey Group 4 First Round |
| 17 | Haddonfield Memorial High School | Haddonfield, New Jersey | 11-8-2 | South Jersey Group 2 Semifinalist |
| 18 | Warren Hills Regional High School | Washington, New Jersey | 15-6-1 | North Jersey Group 3 Semifinalist |
| 19 | Ocean Township High School | Oakhurst, New Jersey | 16-5-0 | South Jersey Group 2 Semifinalist |
| 20 | Wall High School | Wall, New Jersey | 15-3-0 | South Jersey Group 2 Quarterfinalist |
| | | | |
| OC | Northern Highlands High School | Allendale, New Jersey | 18-2-1 | North Jersey Group 3 Quarterfinalist |
| OC | Pompton Lakes High School | Pompton Lakes, New Jersey | 19-2-0 | North Jersey Group 1 Semifinalist |
| OC | Rancocas Valley Regional High School | Mt. Holly, New Jersey | 14-5-0 | South Jersey Group 4 First Round |
| OC | Ridge High School | Basking Ridge, New Jersey | 16-5-1 | North Jersey Group 4 Semifinalist |
2021 NEW JERSEY REGION HIGH SCHOOL
