| 1 | Phillips Andover Academy | Andover, MA | 20-0-0 | 2 | Kate Dolan | NEPSAC A Champions |
| 2 | Somerset Berkley Regional | Somerset, MA | 23-1-0 | 4 | Jen Crook | MIAA Division I State Champions, MIAA South Division I Champions |
| 3 | Biddeford | Biddeford, ME | 17-0-1 | 9 | Caitlin Albert | Maine Class A State Champions (beat Skowhegan 4-3 in final) |
| 4 | Nashoba Regional | Bolton, MA | 20-1-2 | 5 | Jaime Mariani | MIAA Division I State Runner-Up (lost to Somerset Berkley 1-2 OT), MIAA Central Division I Champions |
| 5 | Skowhegan Area | Skowhegan, ME | 17-1-0 | 1 | Paula Doughty | Maine Class A State Runner-Up (lost to Biddeford 4-3 in final) |
| 6 | Walpole | Walpole, MA | 20-2-0 | 3 | Jen Quinn | MIAA South Division I Runner-Up (lost to Somerset Berkley 0-3) |
| 7 | Bellows Falls Union | Westminster, VT | 17-0-0 | 19 | Bethany Coursen | VT Division I State Champions (beat South Burlington 2-0 in final) |
| 8 | Brooks School | North Andover, MA | 17-0-2 | 14 | Ali Mattison | NEPSAC B Champions |
| 9 | Dennis-Yarmouth | South Yarmouth, MA | 21-0-3 | 12 | Mary O'Connor | MIAA Division 2 State Champions, MIAA South Division 2 Champions |
| 10 | Winnacunnet | Hampton, NH | 14-3-0 | 11 | Heidi Hand | NH Division I State Champions (beat Windham 2-0 in final) |
| 11 | Masconomet | Boxford, MA | 19-2-2 | OC | Maggie Bridgeo | MIAA Division I State Semifinalist (lost to Somerset Berkley 0-3), MIAA North Division I Champions |
| 12 | Windham | Windham, NH | 15-2-0 | 13 | Katie Blair | NH Division I State Runner-Up (lost to Winnacunnet 0-2 in final) |
| 13 | King Philip Regional | Wrentham, MA | 18-2-1 | 8 | Liz Hathaway | MIAA South Division I Semifinalist (lost to Somerset Berkley 1-3) |
| 14 | Watertown | Watertown, MA | 19-1-1 | 7 | Eileen Donahue | MIAA Division 2 State Semifinalist (lost to Dennis Yarmouth 1-2), MIAA North Division 2 Champions |
| 15 | Pinkerton Academy | Derry, NH | 14-2-0 | 15 | Courtney Van Nostrand | NH Division I State Semifinalist (lost to Winnacunnet 2-3 in OT SO) |
| 16 | St. Paul's School | Concord, NH | 16-2-1 | 10 | Heather Crutchfield | NEPSAC Class A First Round (lost to Greenwich Academy (CT) 0-1) |
| 17 | Wachusett Regional | Holden, MA | 19-2-0 | NR | Kerry Berry | MIAA Central Division I Runner-Up (lost to Nashoba 2-3) |
| 18 | Westbrook | Westbrook, ME | 14-2-1 | OC | Theresa Hendrix | Maine Class A State Semifinalist (lost to Biddeford 0-1) |
| 19 | Andover | Andover, MA | 14-3-5 | OC | Maureen Noone | MIAA North Division I Runner-Up (lost to Masconomet 1-2 OT) |
| 20 | Acton-Boxborough | Acton, MA | 18-2-0 | 6 | Mae Shoemaker | MIAA North Division I Quarterfinalist (lost to Andover 1-0) |
| | | | | | |
| OC | Chelmsford | North Chelmsford, MA | 14-6-1 | NR | Rebecca Brown | MIAA North Division I Semifinalist (lost to Maconomet 1-4) |
| OC | Colchester | Colchester, VT | 12-1-3 | OC | Katie Comeau | VT Division I State Semifinalist (lost to South Burlington 1-2 in 2OT) |
| OC | Derryfield School | Manchester, NH | 15-1-1 | NR | Lenny McCaigue | NH Division II State Champions (beat Hanover 1-0 in final) |
| OC | Gardiner Area | Gardiner, ME | 17-1-0 | OC | Sharon Gallant | Maine Class B State Champions (beat York 3-2 in final) |
| OC | Longmeadow | Longmeadow, MA | 17-2-2 | 18 | Ann Simons | MIAA Division I State Semifinalist (lost to Nashoba 0-4), MIAA West Division I Champions |
| OC | Manchester Essex Regional | Manchester-by-the-Sea, MA | 16-1-5 | OC | Kara Crovo | MIAA North Division II Runner-Up (lost to Watertown 0-1) |
| OC | Merrimack | Merrimack, NH | 11-4-1 | OC | Ann MacLean | NH Division I Semifinalist (lost to Windham 0-3) |
| OC | Mt. Blue | Farmington, ME | 11-4-2 | OC | Jody Harmon | Maine Class A Semifinalist (lost to Skowhegan 0-3) |
| OC | Noble & Greenough | Dedham, MA | 11-3-3 | 16 | Maura Sullivan | NEPSAC A First Round (lost to Hotchkiss 1-2) |
| OC | Rice Memorial | South Burlington, VT | 10-3-2 | OC | Kelly McClintock | Vermont Division I State Semifinalist (lost to Bellows Falls 2-3) |
| OC | South Burlington | South Burlington, VT | 14-2-1 | 17 | Anjie Soucy | VT Division I State Runner-Up (lost to Bellows Falls 0-2 in final) |
| OC | The River's School | Weston, MA | 15-5-0 | OC | Janna Anctil | NEPSAC B Conference Runner-Up (lost to Brooks School 0-3) |
2018 NEW ENGLAND REGION HIGH SCHOOL
